LET-7B-5P mimic

Intervention

1 paper1 finding

  • 1 lab in 1 country
  • Funders: Canadian Institutes of Health Research and 1 more
  • Humans1

Outcomes

1

IL-1β

downin human cells1

1 study
  1. LET-7B-5P mimic decreases IL-1β in human cells.

    “transfection of IVD cells with let-7b-5p or miR-100-5p mimics individually suppressed IL-1ß expression at both mRNA and protein levels”

    Cellstransfection of IVD cellsintervertebral disc

    Beyond miRNA Cargo Profiles: Anti-Inflammatory Roles of Extracellular Vesicle-Enriched miRNAs Derived From Human Intervertebral Disc Cells Unveiled by Functional Testing

    Journal of extracellular biology7 Apr 2026

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