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KSL0608-SE-MEDIATED photodynamic therapy

Intervention

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Henan Normal University and 3 more
  • Animals1

Outcomes

3

Physical dysfunction

downin mice1

1 study

  1. KSL0608-SE-MEDIATED photodynamic therapy decreases physical dysfunction in mice.

    “inhibited the age-associated physical dysfunction in mice”

    Animalsin naturally-aged mice

    Photoactivatable senolysis with single-cell resolution delays aging

    Nature aging2 Feb 2023

Renal function loss

downin mice1

1 study

  1. KSL0608-SE-MEDIATED photodynamic therapy decreases renal function loss in mice.

    “countered age-induced losses in liver and renal function”

    Animalsin naturally-aged mice

    Photoactivatable senolysis with single-cell resolution delays aging

    Nature aging2 Feb 2023

Senescence-associated secretory phenotype (SASP)

downin mice1

1 study

  1. KSL0608-SE-MEDIATED photodynamic therapy decreases senescence-associated secretory phenotype (SASP) in mice.

    “prevented upregulation of age-related SnCs markers and senescence-associated secretory phenotype factors”

    Animalsin naturally-aged mice

    Photoactivatable senolysis with single-cell resolution delays aging

    Nature aging2 Feb 2023

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