KAI-9531

Intervention

1 paper4 findings

  • 1 lab
  • Human trial1

Outcomes

4

HbA1c

downin humans1

1 study
  1. KAI-9531 decreases HbA1c in humans.

    “Greater reductions in fasting glucose, fasting insulin, and HbA1c were observed with KAI-9531 vs PBO.”

    Human trial29 daysn = 49

    A Phase 1, Randomized, Double-Blind, Single-Ascending Dose Study of KAI-9531, a Novel Dual GLP-1/GIP Receptor Agonist in Development for People Living with Overweight/Obesity

    ADA Scientific Sessions 2026 abstract5 Jun 2026

More on HbA1c

Fasting insulin

downin humans1

1 study
  1. KAI-9531 decreases fasting insulin in humans.

    “Greater reductions in fasting glucose, fasting insulin, and HbA1c were observed with KAI-9531 vs PBO.”

    Human trial29 daysn = 49

    A Phase 1, Randomized, Double-Blind, Single-Ascending Dose Study of KAI-9531, a Novel Dual GLP-1/GIP Receptor Agonist in Development for People Living with Overweight/Obesity

    ADA Scientific Sessions 2026 abstract5 Jun 2026

More on Fasting insulin

Fasting glucose

downin humans1

1 study
  1. KAI-9531 decreases fasting glucose in humans.

    “Greater reductions in fasting glucose, fasting insulin, and HbA1c were observed with KAI-9531 vs PBO.”

    Human trial29 daysn = 49

    A Phase 1, Randomized, Double-Blind, Single-Ascending Dose Study of KAI-9531, a Novel Dual GLP-1/GIP Receptor Agonist in Development for People Living with Overweight/Obesity

    ADA Scientific Sessions 2026 abstract5 Jun 2026

More on Fasting glucose

Body weight

downin humans1

1 study
  1. KAI-9531 decreases body weight in humans (−1.4% to −5.5% vs −0.4% PBO).

    “By EOS, KAI-9531 reduced BW both dose-dependently and compared with PBO, with no differences observed between Asian and non-Asian participants.”

    Human trial29 daysn = 49

    A Phase 1, Randomized, Double-Blind, Single-Ascending Dose Study of KAI-9531, a Novel Dual GLP-1/GIP Receptor Agonist in Development for People Living with Overweight/Obesity

    ADA Scientific Sessions 2026 abstract5 Jun 2026

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