Ion-coupled NAD+ transfersome

1 paper6 findings

1 lab in 1 country

Funders: Gwangju Institute of Science and Technology and 2 more
6 of 6 findings with company ties

Model organisms1

Outcomes

6

Healthspan

upin worms1

1 study

Ion-coupled NAD+ transfersome improves healthspan in worms.
“Moreover, ICoN extends lifespan and enhances healthspan in C. elegans.”
Model organismsion-coupled transfersome
Ion-coupled transfersome complexes for enhanced transdermal NAD⁺ repletion and mitigation of cellular senescence signatures
Materials today. Bio6 May 2026

Lifespan

upin worms1

1 study

Ion-coupled NAD+ transfersome extends lifespan in worms.
“Moreover, ICoN extends lifespan and enhances healthspan in C. elegans.”
Model organismsion-coupled transfersome
Ion-coupled transfersome complexes for enhanced transdermal NAD⁺ repletion and mitigation of cellular senescence signatures
Materials today. Bio6 May 2026

Skin histological disruption

downin human cells1

1 study

Ion-coupled NAD+ transfersome decreases skin histological disruption in human cells.
“ICoN mitigates histological disruption and senescence-associated transcriptional programs at the tissue level.”
CellsUV-stressed human skinion-coupled transfersomeskin
Ion-coupled transfersome complexes for enhanced transdermal NAD⁺ repletion and mitigation of cellular senescence signatures
Materials today. Bio6 May 2026

Mitochondrial functional integrity

upin cells1

1 study

Ion-coupled NAD+ transfersome improves mitochondrial functional integrity in cells.
“ICoN promotes mitochondrial functional integrity and sustains proliferative and migratory competence under senescent and NAD+-depleted conditions.”
Cellssenescent and NAD+-depleted conditionsion-coupled transfersome
Ion-coupled transfersome complexes for enhanced transdermal NAD⁺ repletion and mitigation of cellular senescence signatures
Materials today. Bio6 May 2026

DNA damage-, oxidative stress-, and senescence-associated transcriptomic programs

downin cells1

1 study

Ion-coupled NAD+ transfersome decreases DNA damage-, oxidative stress-, and senescence-associated transcriptomic programs in cells.
“reverses transcriptomic programs associated with DNA damage, oxidative stress, and senescence in vitro.”
Cellsion-coupled transfersome
Ion-coupled transfersome complexes for enhanced transdermal NAD⁺ repletion and mitigation of cellular senescence signatures
Materials today. Bio6 May 2026

More on DNA damage-, oxidative stress-, and senescence-associated transcriptomic programs

Intracellular NAD+

upin cells1

1 study

Ion-coupled NAD+ transfersome increases intracellular NAD+ in cells.
“ICoN restores intracellular NAD+ levels”
Cellsion-coupled transfersome
Ion-coupled transfersome complexes for enhanced transdermal NAD⁺ repletion and mitigation of cellular senescence signatures
Materials today. Bio6 May 2026

More on Intracellular NAD+

Latest

1 in 12 months

Materials Today Bio22 May

Ion-coupled transfersome complexes for enhanced transdermal NAD⁺ repletion and mitigation of cellular senescence signatures

Experiments in wormsInterventions