Intermittent methionine restriction
2 papers6 findings
- 2 independent labs in 1 country
- Funder: National Institute of Diabetes and Digestive and Kidney Diseases
- Animals2
Outcomes
6Dermatitis
downin mice1
1 study
Dermatitis
downin mice1
Intermittent methionine restriction protects against dermatitis in mice.
“high-fat diet-fed mice undergoing both interventions not only have relatively low levels of inflammation, but are also protected against the development of dermatitis.”
Animalshigh-fat diet
Journal of inflammation (London, England)19 Jun 2025
Inflammation
downin mice1
1 study
Inflammation
downin mice1
Intermittent methionine restriction decreases inflammation in mice.
“high-fat diet-fed mice undergoing both interventions not only have relatively low levels of inflammation, but are also protected against the development of dermatitis.”
Animalshigh-fat diet
Journal of inflammation (London, England)19 Jun 2025
Osteoblast count
upin mice1
1 study
Osteoblast count
upin mice1
Intermittent methionine restriction increases osteoblast count in mice.
“increasing the number of osteoblasts.”
Animalscompared with continuous MR
Aging biology23 Jan 2024
Bone strength
upin mice1
1 study
Bone strength
upin mice1
Intermittent methionine restriction improves bone strength in mice.
“the bones of intermittently methionine-restricted mice are significantly stronger than those of mice subjected to the continuous intervention.”
Animalscompared with continuous MR
Aging biology23 Jan 2024
Marrow fat accumulation
downin mice1
1 study
Marrow fat accumulation
downin mice1
Intermittent methionine restriction decreases marrow fat accumulation in mice.
“as well as a dramatic reduction in the accumulation of marrow fat.”
Animalscompared with continuous MR
Aging biology23 Jan 2024
Bone mass
upin mice1
1 study
Bone mass
upin mice1
Intermittent methionine restriction increases bone mass in mice.
“as compared with continuous MR, IMR results in a preservation of both trabecular and cortical bone”
Animalscompared with continuous MR
Aging biology23 Jan 2024