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Interleukin 17b

Intervention

1 paper studies it1 finding

Across all fields, 1 paper: none in people yet, 1 in cells

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Department of Obstetrics and Gynecology, University of Wisconsin-Madison and 1 more
  • Cells1

Outcomes

1

Senescence-associated secretory phenotype (SASP)

upin human cells1

1 study

  1. Interleukin 17b increases senescence-associated secretory phenotype (SASP) in human cells.

    “Stimulation with interleukin 17B enhanced the NF-κB pathway in IL17RB-hEM, resulting in significantly elevated expression of the genes encoding the senescence associated secretory phenotype (SASP) factors IL6, IL8, and IL1β.”

    CellsIL17RB-overexpressing human endometrial glandular epithelial cells (IL17RB-hEM)endometrium

    Endometrial senescence is mediated by interleukin 17 receptor B signaling

    Cell communication and signaling : CCS

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