ESC Congress 2026 Abstract
Proton pump inhibitors linked to more deaths in heart failure
Starting these drugs was associated with 6.66 more cardiovascular events and 5.74 more deaths per 100 patients over five years than not starting acid-suppressing drugs.Starting these drugs was associated with 6.66 more cardiovascular events and 5.74 more deaths per 100 patients over five years than not starting acid-suppressing drugs.

Cohort · 66,834 peopleHeart failure
Who was studied66,834 people with newly diagnosed heart failure, five years, against non-initiators
What changedAll-cause mortality was higher with proton pump inhibitors: 5.74 more deaths per 100 patients compared to non-initiators
The catchThe study included only heart failure patients, not people without heart failure