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Hirudin

Intervention

1 paper studies it3 findings

PubChem

Across all fields, 1 paper: none in people yet, 1 in animals

More peptides

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: National Key Research and Development Program of China and 1 more
  • Animals1

Outcomes

3

Cellular senescence

downin mice1

1 study

  1. Hirudin decreases cellular senescence in mice.

    “hirudin exerted anti-fibrotic, anti-oxidative, and anti-fibroblast senescence effects”

    Animalsin mouse model of pulmonary fibrosislung

    PGC1-Alpha/Sirt3 Signaling Pathway Mediates the Anti-Pulmonary Fibrosis Effect of Hirudin by Inhibiting Fibroblast Senescence

    Biomedicines

More on Cellular senescence

Oxidative stress and ROS signaling

downin mice1

1 study

  1. Hirudin decreases oxidative stress and ROS signaling in mice.

    “hirudin exerted anti-fibrotic, anti-oxidative, and anti-fibroblast senescence effects”

    Animalsin mouse model of pulmonary fibrosislung

    PGC1-Alpha/Sirt3 Signaling Pathway Mediates the Anti-Pulmonary Fibrosis Effect of Hirudin by Inhibiting Fibroblast Senescence

    Biomedicines

More on Oxidative stress and ROS signaling

Pulmonary fibrosis

downin mice1

1 study

  1. Hirudin decreases pulmonary fibrosis in mice.

    “hirudin exerted anti-fibrotic, anti-oxidative, and anti-fibroblast senescence effects”

    Animalsin mouse model of pulmonary fibrosislung

    PGC1-Alpha/Sirt3 Signaling Pathway Mediates the Anti-Pulmonary Fibrosis Effect of Hirudin by Inhibiting Fibroblast Senescence

    Biomedicines

More on Pulmonary fibrosis

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