High-nitrate vegetables

1. High-nitrate vegetables have no effect on redox, inflammatory, and cardiometabolic markers in humans (Between-intervention effect sizes |d| ≤ 0.40).

   “However, this did not translate into significant differences in any redox, inflammatory, or cardiometabolic markers (all p > 0.05).”

   Human trialCompared with low-nitrate vegetables; IL-6 and IL-10 assessed in subsamples of 18 and 35, respectively250 g/day7 daysn = 39

   High- and low-nitrate vegetable intake produce similar effects on redox, inflammatory, and cardiometabolic markers in older adults: a randomized crossover trial

   Nitric oxide : biology and chemistry·15 Oct 2026

More on Redox, inflammatory, and cardiometabolic markers

1. High-nitrate vegetables increase plasma and urinary NOx in humans.

   “substantially increased plasma and urinary NOx concentrations compared to LN (p < 0.001).”

   Human trialCompared with low-nitrate vegetables in community-dwelling older adults250 g/day; measured mean nitrate intake 431.5 ± 163.6 mg/day7 daysn = 39

   High- and low-nitrate vegetable intake produce similar effects on redox, inflammatory, and cardiometabolic markers in older adults: a randomized crossover trial

   Nitric oxide : biology and chemistry·15 Oct 2026

More on Plasma and urinary NOx