GV1001

  • 1 lab in 1 country
  • Funders: Chinese Academy of Medical Sciences Initiative for Innovative Medicine and 4 more
  • Animals1

Outcomes

1

Renal fibrosis

downin mice1

1 study
  1. GV1001 decreases renal fibrosis in mice.

    “GV1001(GV), a peptide fragment derived from human telomerase reverse transcriptase (hTERT), can inhibit the unilateral ureteral obstruction (UUO)-induced renal fibrosis.”

    Animalsunilateral ureteral obstruction-induced renal fibrosiskidney

    The telomerase reverse transcriptase-derived peptide GN11 alleviates glycolysis and cellular senescence in the fibrotic kidney by inhibiting the TGF-β1/Smad3/lncRNA Oip5-os1/miR-30c-5p/Rock2 axis

    Biochemical pharmacology14 Mar 2026

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