GN11

Intervention

1 paper2 findings

  • 1 lab in 1 country
  • Funders: Chinese Academy of Medical Sciences Initiative for Innovative Medicine and 4 more
  • Animals1

Outcomes

2

Glycolysis

downin mice1

1 study
  1. GN11 decreases glycolysis in mice.

    “both GV and its optimized analog GN11 effectively attenuated glycolysis, cellular senescence and apoptotic phenotypes associated with renal fibrosis.”

    Animalsassociated with renal fibrosiskidney

    The telomerase reverse transcriptase-derived peptide GN11 alleviates glycolysis and cellular senescence in the fibrotic kidney by inhibiting the TGF-β1/Smad3/lncRNA Oip5-os1/miR-30c-5p/Rock2 axis

    Biochemical pharmacology14 Mar 2026

More on Glycolysis

Cellular senescence

downin mice1

1 study
  1. GN11 decreases cellular senescence in mice.

    “both GV and its optimized analog GN11 effectively attenuated glycolysis, cellular senescence and apoptotic phenotypes associated with renal fibrosis.”

    Animalsassociated with renal fibrosiskidney

    The telomerase reverse transcriptase-derived peptide GN11 alleviates glycolysis and cellular senescence in the fibrotic kidney by inhibiting the TGF-β1/Smad3/lncRNA Oip5-os1/miR-30c-5p/Rock2 axis

    Biochemical pharmacology14 Mar 2026

More on Cellular senescence

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