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Group IVA phospholipase A2 inhibition

Intervention

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Melanoma Research Alliance and 3 more
  • Animals1

Outcomes

1

Antitumor immunity

upin mice1

1 study

  1. Group IVA phospholipase A2 inhibition improves antitumor immunity in mice.

    “enhanced antitumor immunity and immunotherapy efficacy in mouse models of melanoma and breast cancer in vivo.”

    Animalsin mouse models of melanoma and breast cancer in vivo

    Reprogramming lipid metabolism prevents effector T cell senescence and enhances tumor immunotherapy

    Science translational medicine31 Mar 2021

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