Graptopetalum paraguayense
1 paper5 findings
- 1 lab in 1 country
- Funder: Ministry of Science and Technology, Taiwan
- Model organisms1
Outcomes
5Lifespan
upin worms1
1 study
Lifespan
upin worms1
Graptopetalum paraguayense extends lifespan in worms.
“GP extract significantly extends lifespan in C. elegans.”
Model organisms
Nutrients29 Nov 2021
Physical function
upin worms1
1 study
Physical function
upin worms1
Graptopetalum paraguayense improves physical function in worms.
“GP extract markedly diminishes mobility decline in polyglutamine Q35 mutants and aged wild-type N2 animals in C. elegans.”
Model organismsin polyglutamine Q35 mutants and aged wild-type N2 animals
Nutrients29 Nov 2021
Autophagy
upin worms1
1 study
Autophagy
upin worms1
Graptopetalum paraguayense increases autophagy in worms.
“GP extract enhances autophagy in SH-SYS5Y-APP695 cells, U87 cells, and the nematode Caenorhabditis elegans”
Model organismsin SH-SYS5Y-APP695 cells, U87 cells, and the nematode Caenorhabditis elegans
Nutrients29 Nov 2021
AMPK signalling
upin mice1
1 study
AMPK signalling
upin mice1
Graptopetalum paraguayense activates AMPK signalling in mice.
“AMP-activated protein kinase (AMPK) activity is enhanced by GP extract in U87 cells and APP/PS1 mice.”
Animalsin U87 cells and APP/PS1 mice
Nutrients29 Nov 2021
β-amyloid pathology
downin mice1
1 study
β-amyloid pathology
downin mice1
Graptopetalum paraguayense decreases β-amyloid pathology in mice.
“GP extract suppresses β-amyloid pathology in SH-SYS5Y-APP695 cells and APP/PS1 mice.”
Animalsin SH-SYS5Y-APP695 cells and APP/PS1 mice
Nutrients29 Nov 2021