Germinal vesicle transfer

Germinal vesicle transfer improves full-term development in mammals cells.

“Finally, we show that the overall improved state of the reconstructed oocytes is accompanied by enhanced full-term development.”

Cellsreconstructed oocytesoocyte

Oocyte Age-Dependent DNA Damage Can Be Reverted by the DNA Repair Competent Karyoplasm of Young Oocytes

Aging cell·15 Nov 2025

Germinal vesicle transfer improves fidelity of chromosome segregation in mammals cells.

“This is accompanied by a partial recovery of the chromatin dynamics and, surprisingly, a higher fidelity of chromosome segregation.”

Cellsintroducing GVs of advanced-maternal-age oocytes into DNA repair-competent cytoplasts of young oocytesoocyte

Oocyte Age-Dependent DNA Damage Can Be Reverted by the DNA Repair Competent Karyoplasm of Young Oocytes

Aging cell·15 Nov 2025