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Germ-free rearing

Intervention

2 papers2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Animals2

Outcomes

2

B-cell count

downin rats1

1 study

  1. Germ-free rearing decreases B-cell count in rats.

    “The number of Ts/c and Ts cells were higher in germ-free (GF) vs conventional (CV) rats, whereas B-cell numbers were lower.”

    AnimalsGerm-free versus conventional Lobund-Wistar rats

    Influence of aging, environmental antigens, and dietary restriction on expression of lymphocyte subsets in germ-free and conventional Lobund-Wistar rats

    Journal of gerontology1 May 1991

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Ts/c cell count

upin rats1

1 study

  1. Germ-free rearing increases Ts/c cell count in rats.

    “The number of Ts/c and Ts cells were higher in germ-free (GF) vs conventional (CV) rats, whereas B-cell numbers were lower.”

    AnimalsGerm-free versus conventional Lobund-Wistar rats

    Influence of aging, environmental antigens, and dietary restriction on expression of lymphocyte subsets in germ-free and conventional Lobund-Wistar rats

    Journal of gerontology1 May 1991

More on Ts/c cell count

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