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Folinic acid

Intervention

1 paper studies it1 more mentions it2 findings

PubChemChEBI

Across all fields, 1 paper: none in people yet, 1 in animals

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: China Medical University Hospital and 3 more
  • Animals1

Outcomes

2

Apoptosis

downin mice1

1 study

  1. Folinic acid decreases apoptosis in mice.

    “TUNEL assay and western blot images showed that the number of apoptotic cells and the apoptosis-related protein expression were higher in the Alzheimer's disease group than in other two treated groups.”

    Animalstriple-transgenic late-stage Alzheimer's diseaseheart12 mg/kg3 months

    Folic Acid and Folinic Acid Protect Hearts of Aging Triple-transgenic Alzheimer's Disease mice via IGF1R/PI3K/AKT and SIRT1/AMPK Pathways

    Neurotoxicity research

More on Apoptosis

Heart damage

downin mice1

1 study

  1. Folinic acid prevents heart damage in mice.

    “folic acid and folinic acid promote cardiac cell survival and prevent apoptosis to inhibit heart damage in aging mice with triple-transgenic late-stage Alzheimer's disease”

    Animalstriple-transgenic late-stage Alzheimer's diseaseheart12 mg/kg3 months

    Folic Acid and Folinic Acid Protect Hearts of Aging Triple-transgenic Alzheimer's Disease mice via IGF1R/PI3K/AKT and SIRT1/AMPK Pathways

    Neurotoxicity research

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