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Fn-exo

Intervention

1 paper studies it2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: National Natural Science Foundation of China
  • Animals1

Outcomes

2

DNA damage response

upin human cells1

1 study

  1. Fn-exo induces DNA damage response in human cells.

    “Fn-Exo induces DNA damage via the miR-129-2-3p/TIMELESS axis”

    Cells

    Exosomal-miR-129-2-3p derived from Fusobacterium nucleatum-infected intestinal epithelial cells promotes experimental colitis through regulating TIMELESS-mediated cellular senescence pathway

    Gut microbesJan 1, 2023

More on DNA damage response

Cellular senescence

upin human cells1

1 study

  1. Fn-exo induces cellular senescence in human cells.

    “Fn-Exo induces DNA damage via the miR-129-2-3p/TIMELESS axis and subsequently activates the ATM/ATR/p53 pathway, ultimately promoting cellular senescence and colonic inflammation”

    Cells

    Exosomal-miR-129-2-3p derived from Fusobacterium nucleatum-infected intestinal epithelial cells promotes experimental colitis through regulating TIMELESS-mediated cellular senescence pathway

    Gut microbesJan 1, 2023

More on Cellular senescence

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