Flavin adenine dinucleotide

Flavin adenine dinucleotide has been studied in 2 papers since 2025: none in people yet, 1 in animals, 1 in cells; 1 in the past year. The research so far is in animals and cells. The newest paper, Jul 13, 2026: “Flavin adenine dinucleotide is an endogenous suppressor for cytosolic DNA and RNA sensors to modulate innate immunity”.

2 papers study it17 more mention it1 findingUpdated Jul 13, 2026

PubChem ChEBI MeSH

1 lab in 1 country

Funder: National Natural Science Foundation of China

Animals1
Cells1

What did studies of Flavin adenine dinucleotide find?

1

Studies of Flavin adenine dinucleotide measured 1 outcome; the most studied are sterile inflammation (1 study).

Sterile inflammation

downin mouse cells1

1 study

Flavin adenine dinucleotide prevents sterile inflammation in mouse cells.
“Physiologically, FAD prevented self-nucleic acid-induced sterile inflammation and maintained immune homeostasis.”
Cells
Flavin adenine dinucleotide is an endogenous suppressor for cytosolic DNA and RNA sensors to modulate innate immunity
ImmunityJul 13, 2026

Latest

4 papers in 12 months

Journal of Environmental SciencesSep 1

Simultaneously PYCR-1 and ALH-6 inhibition exacerbates 6-PPD quinone toxicity via disrupting proline and glutamate metabolisms and activating insulin signals in Caenorhabditis elegans

Experiments in wormsAmino acid metabolism

ImmunityJul 14

Flavin adenine dinucleotide is an endogenous suppressor for cytosolic DNA and RNA sensors to modulate innate immunity

Experiments in miceMechanisms

Advances in Wound CareFeb 5

In Vivo, Label-Free Multiphoton Microscopy Is Sensitive to Altered Metabolism and Structure in Aged Skin

Experiments in miceBiomarkers

GeroScienceJan 7

Aging kidney is associated with metabolic rewiring and epigenetic reprogramming

Experiments in miceTryptophan–kynurenine metabolism

npj AgingMay 24

Metabolomics biomarkers of frailty: a longitudinal study of aging female and male mice

Experiments in miceBiomarkers

bioRxivMay 23

Metabolomics biomarkers of frailty: a longitudinal study of aging female and male mice

Preprint: experiments in miceBiomarkers

Scientific ReportsFeb 24

Lysine-specific demethylase 1 (LSD1) suppresses cellular senescence by riboflavin uptake-dependent demethylation activity

Experiments in human cellsCellular senescence

Human ReproductionJul 27

Mitochondria as determinants of reproductive senescence and competence: implications for diagnosis of embryo competence in assisted reproduction

ReviewMitochondrion

GeroScienceJul 18

The mitochondrially targeted peptide elamipretide (SS-31) improves ADP sensitivity in aged mitochondria by increasing uptake through the adenine nucleotide translocator (ANT)

Experiments in animalsInterventions

Aging CellOct 2

Riboflavin depletion promotes longevity and metabolic hormesis in Caenorhabditis elegans

Experiments in wormsMechanisms