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Losartan + fisetin

Intervention

1 paper2 findings

PubChemPubChemChEBIChEBI

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: National Institute of Arthritis and Musculoskeletal and Skin Diseases and 1 more
  • Cells1

Outcomes

2

Stem cell differentiation

upin human cells1

1 study

  1. Losartan + fisetin increases stem cell differentiation in human cells.

    “the combination of 23.6 μM of losartan and 50 μM of fisetin was optimal for reducing cellular senescence and enhancing osteogenesis in BM-MSCs.”

    Cells23.6 μM losartan and 50 μM fisetin24 h

    Combination Therapy of Losartan and Fisetin Reduces Senescence and Enhances Osteogenesis in Human Bone Marrow-Derived Mesenchymal Stem Cells

    Journal of tissue engineering and regenerative medicine19 Mar 2025

More on Stem cell differentiation

Cellular senescence

downin human cells1

1 study

  1. Losartan + fisetin decreases cellular senescence in human cells.

    “the combination of 23.6 μM of losartan and 50 μM of fisetin was optimal for reducing cellular senescence”

    Cells23.6 μM losartan and 50 μM fisetin24 h

    Combination Therapy of Losartan and Fisetin Reduces Senescence and Enhances Osteogenesis in Human Bone Marrow-Derived Mesenchymal Stem Cells

    Journal of tissue engineering and regenerative medicine19 Mar 2025

More on Cellular senescence

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