Fasudil

  • 1 lab in 1 country
  • Funders: National Institutes of Health and 1 more
  • Humans1

Outcomes

2

Inflammation

downin mice1

1 study
  1. Fasudil decreases inflammation in mice.

    “loss of RhoA/ROCK signaling markedly attenuated nasal Th2 inflammation, oxidative stress, and epithelial remodeling following allergen challenge.”

    Animalsfollowing allergen challengenasal mucosa

    Oxidative Stress and PRKN-Mediated Senescence Link RhoA/ROCK Signaling to Epithelial Remodeling in Allergic Rhinitis

    Antioxidants (Basel, Switzerland)7 Jan 2026

More on Inflammation

Epithelial remodeling

downin mice1

1 study
  1. Fasudil decreases epithelial remodeling in mice.

    “loss of RhoA/ROCK signaling markedly attenuated nasal Th2 inflammation, oxidative stress, and epithelial remodeling following allergen challenge.”

    Animalsfollowing allergen challengenasal mucosa

    Oxidative Stress and PRKN-Mediated Senescence Link RhoA/ROCK Signaling to Epithelial Remodeling in Allergic Rhinitis

    Antioxidants (Basel, Switzerland)7 Jan 2026

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