Exercise mimetic extracellular vesicles

Intervention

1 paper6 findings

  • 1 lab in 1 country
  • Animals1

Outcomes

6

Bone mechanical strength

upin mice1

1 study
  1. Exercise mimetic extracellular vesicles improve bone mechanical strength in mice.

    “In aged OSP murine models, DT-EMEVs effectively recovered both bone and muscle mass, enhanced exercise performance, and improved bone mechanical strength.”

    Animalsosteosarcopenia modelmodified with bone-targeting and muscle-targeting peptidesbone

    Dual-targeted exercise mimetic extracellular vesicles regulate the muscle-bone crosstalk to treat osteosarcopenia

    Preprint26 Oct 2025

Exercise performance

upin mice1

1 study
  1. Exercise mimetic extracellular vesicles improve exercise performance in mice.

    “In aged OSP murine models, DT-EMEVs effectively recovered both bone and muscle mass, enhanced exercise performance, and improved bone mechanical strength.”

    Animalsosteosarcopenia modelmodified with bone-targeting and muscle-targeting peptides

    Dual-targeted exercise mimetic extracellular vesicles regulate the muscle-bone crosstalk to treat osteosarcopenia

    Preprint26 Oct 2025

Bone and muscle mass

upin mice1

1 study
  1. Exercise mimetic extracellular vesicles increase bone and muscle mass in mice.

    “In aged OSP murine models, DT-EMEVs effectively recovered both bone and muscle mass”

    Animalsosteosarcopenia modelmodified with bone-targeting and muscle-targeting peptidesbone and skeletal muscle

    Dual-targeted exercise mimetic extracellular vesicles regulate the muscle-bone crosstalk to treat osteosarcopenia

    Preprint26 Oct 2025

Osteogenic differentiation

upin cells1

1 study
  1. Exercise mimetic extracellular vesicles increase osteogenic differentiation in cells.

    “facilitating osteogenic differentiation in vitro”

    Cellsin vitro

    Dual-targeted exercise mimetic extracellular vesicles regulate the muscle-bone crosstalk to treat osteosarcopenia

    Preprint26 Oct 2025

Myotube lifespan

upin cells1

1 study
  1. Exercise mimetic extracellular vesicles increase myotube lifespan in cells.

    “extending the lifespan of myotubes”

    Cellsin vitromyotube

    Dual-targeted exercise mimetic extracellular vesicles regulate the muscle-bone crosstalk to treat osteosarcopenia

    Preprint26 Oct 2025

Muscle stem cell proliferation

upin cells1

1 study
  1. Exercise mimetic extracellular vesicles increase muscle stem cell proliferation in cells.

    “with beneficial effects including promoting the proliferation of muscle stem cells”

    Cellsin vitromuscle stem cell

    Dual-targeted exercise mimetic extracellular vesicles regulate the muscle-bone crosstalk to treat osteosarcopenia

    Preprint26 Oct 2025

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