1 paper1 finding
Intrahepatic fat fraction
no changein humans1
Time-restricted eating + exercise has no effect on intrahepatic fat fraction in humans (−1.1 percentage points versus usual care; 95% CI −2.7 to 0.5; P = 0.28).
“These findings do not support greater short-term IHFF reductions with TRE, exercise, or their combination than with UC or between intervention groups.”
Human trialObesity; compared with usual care consisting of Mediterranean diet and physical activity educationtime-restricted eating combined with supervised exerciseliver8-hour eating window12 weeks
Timed eating and exercise did not beat usual care for liver fat
Nature communications14 Oct 2026
For timed eating, the 12-week liver fat change was 0.4 percentage points lower than with usual care; the range of likely values included no difference.For timed eating, the 12-week liver fat change was 0.4 percentage points lower than with usual care; the range of likely values included no difference.