Etoposide
- 2 independent labs in 2 countries
- 1,348 trials, 464 with no results posted
- Funders: National Institute of Neurological Disorders and Stroke and 1 more
Outcomes
2Senescence-associated marker expression
no changein mouse cells1
1 study
Senescence-associated marker expression
no changein mouse cells1
Etoposide has no effect on senescence-associated marker expression in mouse cells.
“While DNA damage increased after treatment, after 24 h, no change in the expression of senescence-associated markers was observed.”
CellsEtoposide-induced DNA damageprimary neuron24 h
DNA Damage and Senescence in the Aging and Alzheimer's Disease Cortex Are Not Uniformly Distributed
Biomedicines14 Jun 2024
ROCK activity
upin human cells1
1 study
ROCK activity
upin human cells1
Etoposide increases ROCK activity in human cells.
“Induction of cell senescence by etoposide elevates ROCK activity in human preadipocytes”
Cellscell senescence induced by etoposidepreadipocytes
The journals of gerontology. Series A, Biological sciences and medical sciences10 Jan 2024
Trial sponsors
Company12 trialsPhase 35,408 people
Company11 trialsPhase 32,202 people
Company9 trialsPhase 32,001 people
Company6 trialsPhase 32,040 people
Company5 trialsPhase 31,226 people
Company3 trialsPhase 3957 people
Company3 trialsPhase 3796 people
Company3 trialsPhase 3785 people