Prospective memory
upin humans1
Estrone improves prospective memory in humans (Cohen's d = 0.409, p = 0.0353).
“oral E2 and transdermal E1 were associated with higher prospective memory scores (E2: p =0.0353, Cohen’s d =0.296; E1: p =0.0353, Cohen’s d =0.409)”
Humanstransdermalfemales
AAIC 2025 abstract23 Dec 2025
Metabolic dysfunction
upin humans1
Estrone increases metabolic dysfunction in humans.
“emerging evidence suggests that increased E1 levels may contribute to metabolic dysfunction in aging”
Reviewin aging
Frontiers in endocrinology17 Oct 2025
In a nested case-control study of 985 matched pairs, exposure to two common synthetic chemicals was linked to higher type 2 diabetes risk in women.In a nested case-control study of 985 matched pairs, exposure to two common synthetic chemicals was linked to higher type 2 diabetes risk in women.
An observational study of 101 adults aged 30–85 without cognitive impairment found no overall sex differences in a small brain region’s signals or activity.An observational study of 101 adults aged 30–85 without cognitive impairment found no overall sex differences in a small brain region’s signals or activity.