Energy-based devices

3 papers3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Outcomes

Age-related skin changes

upin reviews1

1 study

Energy-based devices improve age-related skin changes.
“Overall, these technologies demonstrated a positive effect on cellular senescence and clinically minimized neocarcinogenesis and improved age-related skin changes.”
Reviewskin
The Impact of Lasers and Energy-Based Devices on Cellular Senescence: A Systematic Review
Lasers in surgery and medicine3 Dec 2025

Cellular senescence

downin reviews1

1 study

Energy-based devices decrease cellular senescence.
“This review suggests that these modalities may reduce cellular senescence, thereby restoring cellular signaling and rejuvenating the skin.”
Reviewskin
The Impact of Lasers and Energy-Based Devices on Cellular Senescence: A Systematic Review
Lasers in surgery and medicine3 Dec 2025

Associations

Neocarcinogenesis

downin reviews1

1 study

Energy-based devices lower the risk of neocarcinogenesis.
“Overall, these technologies demonstrated a positive effect on cellular senescence and clinically minimized neocarcinogenesis and improved age-related skin changes.”
Reviewskin
The Impact of Lasers and Energy-Based Devices on Cellular Senescence: A Systematic Review
Lasers in surgery and medicine3 Dec 2025