Ecdysterone
- 2 independent labs in 2 countries
- Funders: Anhui Provincial Key Research and Development Plan and 1 more
- Animals1
- Model organisms1
Outcomes
4Healthspan
upin worms1
1 study
Healthspan
upin worms1
Ecdysterone improves healthspan in worms.
“treatment with ecdysterone, the most abundant compound in the root extract, improved healthspan by enhancing stress response.”
Model organisms
International journal of molecular sciences15 Apr 2025
Oxidative stress and ROS signalling
downin mice1
1 study
Oxidative stress and ROS signalling
downin mice1
Ecdysterone decreases oxidative stress and ROS signalling in mice.
“decreased oxidative stress, apoptosis and neuronal damage in the hippocampus”
Animalsin SAMP8 micehippocampus
Frontiers in bioscience (Landmark edition)18 Mar 2024
Neuronal damage
downin mice1
1 study
Neuronal damage
downin mice1
Ecdysterone decreases neuronal damage in mice.
“decreased oxidative stress, apoptosis and neuronal damage in the hippocampus”
Animalsin SAMP8 micehippocampus
Frontiers in bioscience (Landmark edition)18 Mar 2024
Learning and memory capabilities
upin mice1
1 study
Learning and memory capabilities
upin mice1
Ecdysterone improves learning and memory capabilities in mice.
“ECR effectively improved cognitive impairment in SAMP8 via enhancement of learning and memory capabilities”
Animalsin SAMP8 micehippocampus
Frontiers in bioscience (Landmark edition)18 Mar 2024
Latest
1 in 12 monthsFrontiers in Bioscience
β-Ecdysterone Attenuates Ang II-Induced Senescence in Human Aortic Smooth Muscle Cells via Autophagy Activation and ROS Suppression Through AKT/mTOR Pathway Inhibition
Experiments in human cellsInterventions
International Journal of Molecular Sciences
Maral Root Extract and Its Main Constituent 20-Hydroxyecdysone Enhance Stress Resilience in Caenorhabditis elegans
Experiments in wormsInterventions