Eccentric cycling

Eccentric cycling has been studied in 6 papers since 2019: 4 trials in people, 1 review; 3 in the past year. The newest paper, Mar 28, 2026: “Eccentric Cycling Improves Motor Learning More Than Concentric Cycling”.

Intervention

6 papers study it5 findingsUpdated

See all 6 papers on eccentric cycling

At a glance

The findings reach people, from one lab or study. 2 independent labs in 2 countries.

“eccentric cycling AAE enhances motor learning more than concentric cycling AAE”
Eccentric Cycling Improves Motor Learning More Than Concentric CyclingScandinavian journal of medicine & science in sports2026doi:10.1111/sms.70262

None of its findings points the other way.

Humans: a single group. Cells, worms or flies and mice: nothing yet.
  • 2 independent labs in 2 countries
  • Funders: Agencia Nacional de Investigación y Desarrollo and 7 more
  • Human trial4

Studies in people

3 studies gave eccentric cycling to people and measured what changed.

What changedDesignPeopleSource

up: Improves motor learningd = -0.537

Trial25 min60 people26.2 ± 3.7 years oldYoung healthy individualsScandinavian journal of medicine & science in sports, Mar 28, 2026

up: Improves physical function

up: Improves cognitive function

Randomized trialeight weeks20 people50.8 ± 8.8 years oldMidlife adults; COVID-19 survivors with post-intensive care syndrome recruited six months after hospitalizationPloS one, Feb 6, 2026

down: Decreases malondialdehyde-22%

Randomized trial30 min10 peopleBoth60.4 ± 6.8 yearsOlder adults; moderate intensity, 50% POmaxEuropean journal of applied physiology, Aug 27, 2019

What did studies of eccentric cycling find?

4

Studies of eccentric cycling measured 4 outcomes; the most studied are motor learning (1 study), cognitive function (1) and physical function (1).

Motor learning

upin humans1

1 study
  1. Eccentric cycling improves motor learning in humans (d = -0.537).

    “Post hoc analyses revealed that the eccentric group performed better than both the concentric (p < 0.001, d = −0.297) and rest (p < 0.001, d = −0.537) groups, while the concentric group demonstrated better performance than the rest group (p < 0.001, d = −0.237; Figure ).”

    Human trial25 minn = 60

    Eccentric Cycling Improves Motor Learning More Than Concentric Cycling

    Scandinavian journal of medicine & science in sports

  2. Eccentric cycling improves motor learning in humans.

    “eccentric cycling AAE enhances motor learning more than concentric cycling AAE”

    Human trial20 minn = 60

    Eccentric Cycling Improves Motor Learning More Than Concentric Cycling

    Scandinavian journal of medicine & science in sports

Cognitive function

upin humans1

1 study
  1. Eccentric cycling improves cognitive function in humans.

    “Eccentric cycling training induced greater functional and cognitive improvements than standard rehabilitation.”

    Human trialCOVID-19 survivors with post-intensive care syndrome recruited six months after hospitalizationeight weeksn = 20

    Eccentric cycling is superior to standard rehabilitation for Post-ICU recovery in COVID-19 survivors

    PloS one

Physical function

upin humans1

1 study
  1. Eccentric cycling improves physical function in humans.

    “ECC showed larger improvements in 6MWT, TUG, and Barthel Index compared to STD REHAB.”

    Human trialCOVID-19 survivors with post-intensive care syndrome recruited six months after hospitalizationeight weeksn = 20

    Eccentric cycling is superior to standard rehabilitation for Post-ICU recovery in COVID-19 survivors

    PloS one

Malondialdehyde

downin humans1−22%

1 study
  1. Eccentric cycling decreases malondialdehyde in humans (moderate intensity, 50% POmax) (-22%).

    “MDA decreased (P < 0.05) after CONC-M (- 28%) and ECC-M (- 22%), but not after ECC-H.”

    Human trialmoderate intensity, 50% POmax50% POmax30 min

    Changes in oxidative stress, inflammation and muscle damage markers following eccentric versus concentric cycling in older adults

    European journal of applied physiology

More on Malondialdehyde

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Dec 2025: 0Jan 2026: 1Feb 2026: 1Mar 2026: 1Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 0Nov 2026: 03 papers in 12 months