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Early time-restricted feeding

Intervention

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: National Center for Advancing Translational Sciences and 5 more
  • Animals1

Outcomes

3

Body composition

no changein N. primates1

1 study

  1. Early time-restricted feeding has no effect on body composition in N. primates.

    “without changes in glycemic control or body composition”

    Animals12 months

    Early time-restricted feeding improves high-density lipoprotein amount and function in nonhuman primates, without effects on body composition

    Obesity (Silver Spring, Md.)13 Oct 2022

Triglyceride

downin N. primates1

1 study

  1. Early time-restricted feeding decreases triglyceride in N. primates.

    “lowered triglyceride concentrations”

    Animals12 months

    Early time-restricted feeding improves high-density lipoprotein amount and function in nonhuman primates, without effects on body composition

    Obesity (Silver Spring, Md.)13 Oct 2022

More on Triglyceride

Cholesterol efflux capacity

upin N. primates1

1 study

  1. Early time-restricted feeding increases cholesterol efflux capacity in N. primates.

    “eTRF induced larger-sized HDL particles, increased HDL apolipoprotein A-1 content, lowered triglyceride concentrations, and increased plasma CEC (primarily to HDL particles) in both adult and geriatric NHPs”

    Animals12 months

    Early time-restricted feeding improves high-density lipoprotein amount and function in nonhuman primates, without effects on body composition

    Obesity (Silver Spring, Md.)13 Oct 2022

More on Cholesterol efflux capacity

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