Early diet switch

1. Early diet switch increases TNF-alpha in mice (~2-fold).

   “Significant increases in TNFα expression were detectable in the intestinal tract of the Switch group (∼2-fold), suggesting a higher sensitivity to inflammation perhaps related to the timing of the diet change.”

   Animalsintestinal tract

   Early- and life-long intake of dietary advanced glycation end-products (dAGEs) leads to transient tissue accumulation, increased gut sensitivity to inflammation, and slight changes in gut microbial diversity, without causing overt disease

   Food research international (Ottawa, Ont.)·Aug 23, 2024

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