AgingResearch.NewsJoin free

Dietary carboxymethyl-lysine

Intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Agence Nationale de la Recherche and 1 more
  • Animals1

Outcomes

2

Inflammation

no changein mice1

1 study

  1. Dietary carboxymethyl-lysine has no effect on inflammation in mice.

    “The dCML-enriched diet had no significative effect on endogenous glycation, inflammation, oxidative stress or senescence parameters.”

    Animals70 weeks

    Early- and life-long intake of dietary advanced glycation end-products (dAGEs) leads to transient tissue accumulation, increased gut sensitivity to inflammation, and slight changes in gut microbial diversity, without causing overt disease

    Food research international (Ottawa, Ont.)Aug 23, 2024

More on Inflammation

N(6)-carboxymethyllysine

upin mice1

1 study

  1. Dietary carboxymethyl-lysine increases N(6)-carboxymethyllysine in mice (3-fold, 17-fold and 20-fold increases).

    “significant RAGE-independent accumulation of dCML in kidneys, ileum and colon over the 70-week dietary intervention (respectively 3-fold, 17-fold and 20-fold increases compared with controls).”

    Animalskidneys, ileum and colon70 weeks

    Early- and life-long intake of dietary advanced glycation end-products (dAGEs) leads to transient tissue accumulation, increased gut sensitivity to inflammation, and slight changes in gut microbial diversity, without causing overt disease

    Food research international (Ottawa, Ont.)Aug 23, 2024

More on N(6)-carboxymethyllysine

Latest

Related