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Drosophila a virus infection

Drosophila a virus infection has been studied in 1 paper since 2023: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Nov 16, 2023: “Viral infection disrupts intestinal homeostasis via Sting-dependent NF-kB signaling”.

Exposure

1 paper studies it2 findingsUpdated

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: Agence Nationale de la Recherche and 1 more
  • 2 of 2 findings with company ties
  • Model organisms1

What did studies of Drosophila a virus infection find?

2

Studies of Drosophila a virus infection measured 2 outcomes; the most studied are lifespan (1 study) and intestinal stem cell proliferation (1).

Lifespan

downin flies1

1 study

  1. Drosophila a virus infection shortens lifespan in flies.

    “Drosophila A virus (DAV) infection disrupts intestinal homeostasis in Drosophila by inducing sustained ISC proliferation, resulting in intestinal dysplasia, loss of gut barrier function, and reduced lifespan.”

    Model organismsintestine

    Viral infection disrupts intestinal homeostasis via Sting-dependent NF-kB signaling

    bioRxiv (Cold Spring Harbor Laboratory)Preprint

Intestinal stem cell proliferation

upin flies1

1 study

  1. Drosophila a virus infection induces intestinal stem cell proliferation in flies.

    “Drosophila A virus (DAV) infection disrupts intestinal homeostasis in Drosophila by inducing sustained ISC proliferation, resulting in intestinal dysplasia, loss of gut barrier function, and reduced lifespan.”

    Model organismsintestine

    Viral infection disrupts intestinal homeostasis via Sting-dependent NF-kB signaling

    bioRxiv (Cold Spring Harbor Laboratory)Preprint

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