Dichlorodiphenyltrichloroethane
Dichlorodiphenyltrichloroethane has been studied in 3 papers since 2021: 3 observational studies in people. The newest paper, Mar 15, 2024: “Gender- and Age-Group Specific Association of Persistent Organic Pollutants (POPs) Exposure with Diabetes Mellitus: Korean National Environmental Health Survey (KoNEHS) 2015-2017”.
None of its findings points the other way.
- 1 lab in 1 country
- Funders: National Institute of Environmental Health Sciences and 3 more
- Humans3
What did studies of Dichlorodiphenyltrichloroethane find?
6Studies of Dichlorodiphenyltrichloroethane measured 6 outcomes; the most studied are growth (2 studies), mitochondrial function (1) and curling (1).
Growth
downin worms2
2 studies
Growth
downin worms2
Dichlorodiphenyltrichloroethane decreases growth in worms.
“DDT exacerbated the inhibitory effect of p-tau protein on growth and basal respiration.”
Model organismstransgenic strain expressing human tau protein
Cross-species metabolomic analysis of tau- and DDT-related toxicity
PNAS nexus
Dichlorodiphenyltrichloroethane decreases growth in worms.
“DDT exacerbated the inhibitory effect of aggregating tau protein on growth and basal respiration.”
Model organismsin the presence of aggregating tau protein
Cross-species metabolomic analysis of DDT and Alzheimer’s disease-associated tau toxicity
bioRxiv (Cold Spring Harbor Laboratory)Preprint
Mitochondrial function
downin worms1
1 study
Mitochondrial function
downin worms1
Dichlorodiphenyltrichloroethane inhibits mitochondrial function in worms.
“DDT exposure can exacerbate the mitochondrial inhibitory effects of p-tau aggregation.”
Model organismsp-tau aggregation
Cross-species metabolomic analysis of tau- and DDT-related toxicity
PNAS nexus
Curling
upin worms1
1 study
Curling
upin worms1
Dichlorodiphenyltrichloroethane increases curling in worms.
“In the presence of p-tau protein, DDT induced more curling and was associated with reduced levels of amino acids”
Model organismsin the presence of p-tau protein
Cross-species metabolomic analysis of tau- and DDT-related toxicity
PNAS nexus
Respiration
downin worms1
1 study
Respiration
downin worms1
Dichlorodiphenyltrichloroethane decreases respiration in worms.
“DDT exacerbated the inhibitory effect of p-tau protein on growth and basal respiration.”
Model organismstransgenic strain expressing human tau protein
Cross-species metabolomic analysis of tau- and DDT-related toxicity
PNAS nexus
Curling behavior
upin worms1
1 study
Curling behavior
upin worms1
Dichlorodiphenyltrichloroethane increases curling behavior in worms.
“In the presence of aggregating tau protein, DDT induced more curling”
Model organismsin the presence of aggregating tau protein
Cross-species metabolomic analysis of DDT and Alzheimer’s disease-associated tau toxicity
bioRxiv (Cold Spring Harbor Laboratory)Preprint
Basal respiration
downin worms1
1 study
Basal respiration
downin worms1
Dichlorodiphenyltrichloroethane decreases basal respiration in worms.
“DDT exacerbated the inhibitory effect of aggregating tau protein on growth and basal respiration.”
Model organismsin the presence of aggregating tau protein
Cross-species metabolomic analysis of DDT and Alzheimer’s disease-associated tau toxicity
bioRxiv (Cold Spring Harbor Laboratory)Preprint