Deoxyribonuclease i

Deoxyribonuclease i improves spatial learning and memory in mice.

“DNase I restores meningeal lymphatic function and ameliorates spatial learning and memory deficits in aged mice.”

Animals

Aging-Associated CCL8⁺ Senescent Macrophages Recruit CCR1⁺ Neutrophils to Promote NETs Formation and Impair Meningeal Lymphatic Drainage

Aging and disease·29 Apr 2026

Deoxyribonuclease i improves meningeal lymphatic function in mice.

“enzymatic degradation of NETs with DNase I restores meningeal lymphatic function”

Animalsmeningeal lymphatic vessels

Aging-Associated CCL8⁺ Senescent Macrophages Recruit CCR1⁺ Neutrophils to Promote NETs Formation and Impair Meningeal Lymphatic Drainage

Aging and disease·29 Apr 2026