Daphnetin
- 1 lab in 1 country
- Funders: China Postdoctoral Science Foundation and 4 more
- Animals1
Outcomes
3Bone resorption
downin mice1
1 study
Bone resorption
downin mice1
Daphnetin decreases bone resorption in mice.
“resulting in attenuation of osteoclast differentiation and bone resorption”
Animalsin disuse osteoporosis / osteoclasts
Antioxidants (Basel, Switzerland)
Bone formation
upin mice1
1 study
Bone formation
upin mice1
Daphnetin increases bone formation in mice.
“daphnetin inhibited NOX2-mediated ROS production in osteoblasts, resulting in accelerated osteogenic differentiation and bone formation”
Animalsin senile osteoporosis / osteoblasts
Antioxidants (Basel, Switzerland)
Osteoporosis
downin mice1
1 study
Osteoporosis
downin mice1
Daphnetin protects against osteoporosis in mice.
“daphnetin administration effectively improved bone remodeling in both senile and disuse osteoporosis”
Animalsin SAMP8 mice and hindlimb unloading mice
Antioxidants (Basel, Switzerland)