Dairy

4 papers3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country
1 finding against

Funders: Aalborg Universitet and others

Humans3

Outcomes

Systolic blood pressure

downin humans1no changein humans1

1 study

Dairy decreases systolic blood pressure in humans (-0.11, 95% CI -0.20 to -0.02 mm Hg).
“In observational analysis, each serving/day increase in dairy consumption was associated with -0.11 (95% confidence interval -0.20 to -0.02 mm Hg; P=0.02) lower systolic blood pressure”
Humanseach serving/day increase
Dairy consumption, systolic blood pressure, and risk of hypertension: Mendelian randomization study
BMJ (Clinical research ed.)16 Mar 2017
Dairy has no effect on systolic blood pressure in humans (β=1.35, 95% CI -0.28 to 2.97 mm Hg).
“genetically determined dairy consumption was not associated with systolic blood pressure (β=1.35, 95% confidence interval -0.28 to 2.97 mm Hg for each serving/day)”
Humansinstrumental variable analysis (LCT-13910 rs4988235)
Dairy consumption, systolic blood pressure, and risk of hypertension: Mendelian randomization study
BMJ (Clinical research ed.)16 Mar 2017