Conditioned media from synovial fluid-stimulated umbilical cord-derived mesenchymal stem cells
Conditioned media from synovial fluid-stimulated umbilical cord-derived mesenchymal stem cells has been studied in 1 paper since 2024: none in people yet, 1 in cells. No study of it in people or animals has been published yet. The newest paper, Nov 12, 2024: “Effects of Conditioned Media From Human Umbilical Cord-Derived Mesenchymal Stem Cells on Tenocytes From Degenerative Rotator Cuff…”.
1 paper studies it4 findingsUpdated
None of its findings points the other way.
- 1 lab in 1 country
- Funders: American Orthopaedic Society for Sports Medicine and 4 more
- Cells1
What did studies of Conditioned media from synovial fluid-stimulated umbilical cord-derived mesenchymal stem cells find?
4Studies of Conditioned media from synovial fluid-stimulated umbilical cord-derived mesenchymal stem cells measured 4 outcomes; the most studied are type I/III collagen ratio (1 study), apoptosis (1) and cellular senescence (1).
Type I/III collagen ratio
upin human cells1
1 study
Type I/III collagen ratio
upin human cells1
Conditioned media from synovial fluid-stimulated umbilical cord-derived mesenchymal stem cells increase type I/III collagen ratio in human cells.
“It did increase the type I/III ratio of gene expression and protein synthesis, mainly through the induction of type I collagen.”
Cellsin IL-1β-treated tenocytes from degenerative rotator cuff tearstenocytes50%
Orthopaedic journal of sports medicine
Apoptosis
downin human cells1
1 study
Apoptosis
downin human cells1
Conditioned media from synovial fluid-stimulated umbilical cord-derived mesenchymal stem cells decrease apoptosis in human cells.
“Conditioned media of SF-UC-MSCs reversed senescence and apoptosis induced by IL-1β.”
Cellsin IL-1β-treated tenocytes from degenerative rotator cuff tearstenocytes50%
Orthopaedic journal of sports medicine
Cellular senescence
downin human cells1
1 study
Cellular senescence
downin human cells1
Conditioned media from synovial fluid-stimulated umbilical cord-derived mesenchymal stem cells decrease cellular senescence in human cells.
“Conditioned media of SF-UC-MSCs reversed senescence and apoptosis induced by IL-1β.”
Cellsin IL-1β-treated tenocytes from degenerative rotator cuff tearstenocytes50%
Orthopaedic journal of sports medicine
Prostaglandin E2
downin human cells1
1 study
Prostaglandin E2
downin human cells1
Conditioned media from synovial fluid-stimulated umbilical cord-derived mesenchymal stem cells decrease prostaglandin E2 in human cells.
“Meanwhile, the conditioned media decreased the PGE2 level on cells induced by IL-1β.”
Cellsin IL-1β-treated tenocytes from degenerative rotator cuff tearstenocytes50%
Orthopaedic journal of sports medicine