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Compound 11a

Intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Basic and Applied Basic Research Foundation of Guangdong Province and 4 more
  • Animals1

Outcomes

2

Cognitive function

upin mice1

1 study

  1. Compound 11a improves cognitive function in mice.

    “Feeding NMN or #11a substantially ameliorates the cognitive and motor impairments of Thy 1-C/EBPβ mice and increases the life expectancy.”

    Animalsin Thy 1-C/EBPβ mice

    Neuronal C/EBPβ Shortens the Lifespan via Inactivating NAMPT

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)30 Apr 2025

Lifespan

upin mice1

1 study

  1. Compound 11a extends lifespan in mice.

    “Feeding NMN or #11a substantially ameliorates the cognitive and motor impairments of Thy 1-C/EBPβ mice and increases the life expectancy.”

    Animalsin Thy 1-C/EBPβ mice

    Neuronal C/EBPβ Shortens the Lifespan via Inactivating NAMPT

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)30 Apr 2025

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