Composite dietary antioxidant index

1. Composite dietary antioxidant index is associated with brain volume in humans.

   “CDAI was positively associated with cortical and subcortical volumes in the lower CDAI group after Bonferroni correction.”

   Humansin the lower CDAI group

   L‐Shaped Association Between Composite Dietary Antioxidant Index and Risk of Dementia: Results from a Prospective Cohort Study

   AAIC 2025 abstract·23 Dec 2025

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1. Composite dietary antioxidant index lowers the risk of Alzheimer's disease in humans (HR 0.935, 95% CI: 0.897-0.974).

   “and a 6.5% reduced risk of AD (HR, 0.935; 95% CI: 0.897‐0.974, p = 0.001).”

   Humansbelow inflection point (0.848)per unit increase

   L‐Shaped Association Between Composite Dietary Antioxidant Index and Risk of Dementia: Results from a Prospective Cohort Study

   AAIC 2025 abstract·23 Dec 2025

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1. Composite dietary antioxidant index lowers the risk of dementia in humans (HR 0.937, 95% CI: 0.907-0.968).

   “Below the inflection points, each unit increase in CDAI was associated with a 6.3% reduced risk of all‐cause dementia (HR, 0.937; 95% CI: 0.907‐0.968, p < 0.001)”

   Humansbelow inflection point (1.579)per unit increase

   L‐Shaped Association Between Composite Dietary Antioxidant Index and Risk of Dementia: Results from a Prospective Cohort Study

   AAIC 2025 abstract·23 Dec 2025

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1. Composite dietary antioxidant index is associated with gout in humans (OR 0.32, 95% CI = 0.09-0.96, P = 0.055).

   “those with positive CDAI had a marginally significant 68% reduction in the odds of developing gout compared to those with negative CDAI (OR 0.32, 95% CI = 0.09-0.96, P = 0.055).”

   Humansamong patients with hyperuricemia

   Biological aging and gout risk in hyperuricemia: a UK Biobank cohort study

   International journal of surgery (London, England)·28 Nov 2025

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