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Combined metabolic activators

Intervention

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 2 countries
  • Funders: European Commission and 3 more
  • Animals1

Outcomes

3

Liver metabolic function

upin rats1

1 study

  1. Combined metabolic activators improve liver metabolic function in rats.

    “notable metabolic enhancements in liver tissues were observed using both formulations”

    Animalsin animal models of AD and PDliver

    Combined Metabolic Activators with Different NAD+ Precursors Improve Metabolic Functions in the Animal Models of Neurodegenerative Diseases

    BiomedicinesApr 22, 2024

Behavioral function

upin rats1

1 study

  1. Combined metabolic activators improve behavioral function in rats.

    “In PD rat models, the administration of both formulations positively influenced the behavioral functions of the animals.”

    Animalsin PD rat models

    Combined Metabolic Activators with Different NAD+ Precursors Improve Metabolic Functions in the Animal Models of Neurodegenerative Diseases

    BiomedicinesApr 22, 2024

Neuronal necrosis

downin rats1

1 study

  1. Combined metabolic activators decrease neuronal necrosis in rats.

    “administration of both CMA1 and CMA2 formulations led to improvements in hyperemia, degeneration, and necrosis in neurons for both AD and PD models”

    Animalsin animal models of AD and PDbrain

    Combined Metabolic Activators with Different NAD+ Precursors Improve Metabolic Functions in the Animal Models of Neurodegenerative Diseases

    BiomedicinesApr 22, 2024

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