Cognitively stimulating activities

Exposure

6 papers4 findings

  • 4 independent labs in 1 country
  • Funders: National Institute on Aging and 2 more
  • Humans5

Outcomes

2

Cognitive function

upin humans1

1 study
  1. Cognitively stimulating activities improve cognitive function in humans.

    “Greater cognitive activity was specifically associated with better executive functioning, episodic memory, and language scores.”

    Humansn = 314

    Pathway analysis of cognitive resilience factors and cognitive function in the Long Life Family Study (LLFS)

    Neuropsychology29 Sep 2025

Decline in processing speed

downin humans1

1 study
  1. Cognitively stimulating activities decrease decline in processing speed in humans.

    “attenuated the effects of change in cortical thickness and brain volume on decline in processing speed over time”

    Humanshigher childhood CSAn = 204

    Childhood engagement in cognitively stimulating activities moderates relationships between brain structure and cognitive function in adulthood

    Neurobiology of aging23 Feb 2024

Associations

2

Subjective cognitive concerns

downin humans1

1 study
  1. Cognitively stimulating activities are associated with subjective cognitive concerns in humans (B=-0.05, 95% CI -0.08 to -0.02).

    “cognitively stimulating activities (B=-0.05, 95% CI -0.08 to -0.02; P<.001)”

    Humansmild-to-moderate chronic stroke2 weeksn = 202

    Real-Time Associations Between Subjective Cognitive Concerns and Daily Activity Participation in Persons Aging With Stroke: Smartphone-Based Ecological Momentary Assessment Study

    JMIR aging14 Jul 2026

Cognitive resilience

upin humans1

1 study
  1. Cognitively stimulating activities are associated with cognitive resilience in humans.

    “When examining the individual LIBRA components simultaneously, cognitively stimulating activities showed the strongest associations with both CR measures”

    Humans71% femalesn = 585

    Associations of the LIfestyle for BRAin health index with Cognitive Resilience to neuropathology

    AAIC 2025 abstract23 Dec 2025

Funding

2 grants since 2017

Japan Society for the Promotion of ScienceJP¥6.3m

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