AgingResearch.NewsJoin free

COG1410

Intervention

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: National Natural Science Foundation of China
  • Animals1

Outcomes

3

Apoptosis

downin mice1

1 study

  1. COG1410 decreases apoptosis in mice.

    “Pre-treatment with COG1410 effectively reduced these pro-inflammatory and pro-apoptotic markers, while alleviating cognitive impairment.”

    Animalsfollowing surgery

    TREM2 Modulates Postoperative Cognitive Function in Aged Mice by Inhibiting the NLRP3/caspase-1 Pathway and Apoptosis via PLCγ2 Activation

    Molecular neurobiology12 Mar 2025

More on Apoptosis

Inflammation

downin mice1

1 study

  1. COG1410 decreases inflammation in mice.

    “Pre-treatment with COG1410 effectively reduced these pro-inflammatory and pro-apoptotic markers, while alleviating cognitive impairment.”

    Animalsfollowing surgery

    TREM2 Modulates Postoperative Cognitive Function in Aged Mice by Inhibiting the NLRP3/caspase-1 Pathway and Apoptosis via PLCγ2 Activation

    Molecular neurobiology12 Mar 2025

More on Inflammation

Cognitive impairment

upin mice1

1 study

  1. COG1410 improves cognitive impairment in mice.

    “Pre-treatment with COG1410 effectively reduced these pro-inflammatory and pro-apoptotic markers, while alleviating cognitive impairment.”

    Animalsfollowing surgery

    TREM2 Modulates Postoperative Cognitive Function in Aged Mice by Inhibiting the NLRP3/caspase-1 Pathway and Apoptosis via PLCγ2 Activation

    Molecular neurobiology12 Mar 2025

Latest

Related