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Coenzyme Q10 + physical exercise

Intervention

1 paper studies it4 findings

Across all fields, 1 paper: none in people yet, 1 in animals

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab
  • Animals1

Outcomes

4

Apoptosis

downin mice1

1 study

  1. Coenzyme Q10 + physical exercise decreases apoptosis in mice.

    “Accordingly, combination treatment while promoting mitochondrial biogenesis lowered autophagy and caspase 3-dependent apoptosis.”

    AnimalsSAMP8 mice in the presarcopenia phase; caspase 3-dependent apoptosisubiquinolskeletal muscle2 months

    Combination of Coenzyme Q₁₀ Intake and Moderate Physical Activity Counteracts Mitochondrial Dysfunctions in a SAMP8 Mouse Model

    Oxidative medicine and cellular longevity

More on Apoptosis

Autophagy

downin mice1

1 study

  1. Coenzyme Q10 + physical exercise decreases autophagy in mice.

    “Accordingly, combination treatment while promoting mitochondrial biogenesis lowered autophagy and caspase 3-dependent apoptosis.”

    AnimalsSAMP8 mice in the presarcopenia phaseubiquinolskeletal muscle2 months

    Combination of Coenzyme Q₁₀ Intake and Moderate Physical Activity Counteracts Mitochondrial Dysfunctions in a SAMP8 Mouse Model

    Oxidative medicine and cellular longevity

More on Autophagy

Mitochondrial biogenesis (PGC-1α)

upin mice1

1 study

  1. Coenzyme Q10 + physical exercise increases mitochondrial biogenesis (PGC-1α) in mice.

    “Accordingly, combination treatment while promoting mitochondrial biogenesis lowered autophagy and caspase 3-dependent apoptosis.”

    AnimalsSAMP8 mice in the presarcopenia phaseubiquinolskeletal muscle2 months

    Combination of Coenzyme Q₁₀ Intake and Moderate Physical Activity Counteracts Mitochondrial Dysfunctions in a SAMP8 Mouse Model

    Oxidative medicine and cellular longevity

More on Mitochondrial biogenesis (PGC-1α)

Mitochondrial damage

downin mice1

1 study

  1. Coenzyme Q10 + physical exercise decreases mitochondrial damage in mice.

    “significantly improved the overall status of the skeletal muscle, preserving mitochondrial ultrastructure and limiting mitochondrial depolarization induced by physical exercise alone.”

    AnimalsSAMP8 mice in the presarcopenia phase; compared with physical exercise aloneubiquinolskeletal muscleubiquinol 500 mg/kg/day; exercise 0.5 km/h, 5% inclination, 30 min, 5/7 days per week2 months

    Combination of Coenzyme Q₁₀ Intake and Moderate Physical Activity Counteracts Mitochondrial Dysfunctions in a SAMP8 Mouse Model

    Oxidative medicine and cellular longevity

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