Citric acid

1. Citric acid improves royal jelly quality in A. mellifera.

   “Colonies consuming feed containing 0.50% CA produced royal jelly with significantly reduced moisture and total sugar content and increased levels of 10-HDA, total phenolic acids, total proteins, and acidity.”

   Model organismsin feed0.50%

   Consumption of Citric Acid by Bees Promotes the Gland Development and Enhances Royal Jelly Quality

   Life (Basel, Switzerland)·Mar 6, 2024

1. Citric acid improves gland development in A. mellifera.

   “Gland development in bees showed a positive correlation with CA addition within the range of 0.25% to 0.75%”

   Model organismsin feed0.25% to 0.75%

   Consumption of Citric Acid by Bees Promotes the Gland Development and Enhances Royal Jelly Quality

   Life (Basel, Switzerland)·Mar 6, 2024

1. Citric acid increases pollen consumption in A. mellifera.

   “feed containing 0.75% CA significantly extended the lifespan of bees and increased their pollen consumption.”

   Model organismsin feed0.75%

   Consumption of Citric Acid by Bees Promotes the Gland Development and Enhances Royal Jelly Quality

   Life (Basel, Switzerland)·Mar 6, 2024

1. Citric acid extends lifespan in A. mellifera.

   “feed containing 0.75% CA significantly extended the lifespan of bees”

   Model organismsin feed0.75%

   Consumption of Citric Acid by Bees Promotes the Gland Development and Enhances Royal Jelly Quality

   Life (Basel, Switzerland)·Mar 6, 2024

1. Citric acid induces cellular senescence in mouse cells.

   “co-inhibition of Idh3α and CIC with shRNA or inhibitors triggered the senescence of AECs, indicating that accumulated citratemt triggers AEC senescence.”

   Cellsco-inhibition of Idh3a and Slc25a1 with shRNA or inhibitors

   Mitochondrial citrate accumulation triggers senescence of alveolar epithelial cells contributing to pulmonary fibrosis in mice

   Heliyon·Jun 19, 2023

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