Cinnamic acid

2 papers4 findings

1 lab in 1 country

Funders: Center for Information Technology and 3 more

Animals1
In silico1

Outcomes

4

Lifespan

upin mice1

1 study

Cinnamic acid extends lifespan in mice.
“increased the survival of Sandhoff mice”
Animalsin Sandhoff mice
Cinnamic acid, a natural plant compound, exhibits neuroprotection in a mouse model of Sandhoff disease via PPARα
NeuroImmune pharmacology and therapeutics15 Mar 2024

Behavioral performance

upin mice1

1 study

Cinnamic acid improves behavioral performance in mice.
“Besides, oral CA also improved behavioral performance and increased the survival of Sandhoff mice.”
Animalsin Sandhoff mice
Cinnamic acid, a natural plant compound, exhibits neuroprotection in a mouse model of Sandhoff disease via PPARα
NeuroImmune pharmacology and therapeutics15 Mar 2024

GM2 ganglioside

downin mice1

1 study

Cinnamic acid decreases GM2 ganglioside in mice.
“reduced the accumulation of GM2 gangliosides/glycoconjugates in the cerebral cortex of Sandhoff mice”
Animalsin Sandhoff micecerebral cortex
Cinnamic acid, a natural plant compound, exhibits neuroprotection in a mouse model of Sandhoff disease via PPARα
NeuroImmune pharmacology and therapeutics15 Mar 2024

More on GM2 ganglioside

Inflammation

downin mice1

1 study

Cinnamic acid decreases inflammation in mice.
“Oral administration of CA significantly attenuated glial activation and inflammation”
Animalsin a transgenic mouse model of SDcerebral cortex
Cinnamic acid, a natural plant compound, exhibits neuroprotection in a mouse model of Sandhoff disease via PPARα
NeuroImmune pharmacology and therapeutics15 Mar 2024

More on Inflammation

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