Chitosan-rapamycin carbon dots

Intervention

1 paper4 findings

  • 1 lab in 1 country
  • Funders: Heilongjiang Provincial Science and Technology Department and 2 more
  • Animals1

Outcomes

4

Oxidative stress and ROS signalling

downin mouse cells1

1 study
  1. Chitosan-rapamycin carbon dots decrease oxidative stress and ROS signalling in mouse cells.

    “CRCD pretreatment enhanced autophagy, reduced oxidative stress, and augmented paracrine neurotrophic release.”

    Cellsin aged OPTN(E50K) bone marrow stem cells

    Chitosan-rapamycin carbon dots rejuvenate autologous Sca-1⁺ stem cells paracrine function for neuroprotection in normal tension glaucoma

    Stem cell research & therapy23 Feb 2026

More on Oxidative stress and ROS signalling

Autophagy

upin mouse cells1

1 study
  1. Chitosan-rapamycin carbon dots increase autophagy in mouse cells.

    “CRCD pretreatment enhanced autophagy, reduced oxidative stress, and augmented paracrine neurotrophic release.”

    Cellsin aged OPTN(E50K) bone marrow stem cells

    Chitosan-rapamycin carbon dots rejuvenate autologous Sca-1⁺ stem cells paracrine function for neuroprotection in normal tension glaucoma

    Stem cell research & therapy23 Feb 2026

More on Autophagy

Apoptosis

downin mouse cells1

1 study
  1. Chitosan-rapamycin carbon dots decrease apoptosis in mouse cells.

    “In vitro, these cells reduced retinal ganglion cell apoptosis and promoted neurotrophic factor expression in co-cultured retinal explants.”

    Cellsin co-cultured retinal explantsretina

    Chitosan-rapamycin carbon dots rejuvenate autologous Sca-1⁺ stem cells paracrine function for neuroprotection in normal tension glaucoma

    Stem cell research & therapy23 Feb 2026

More on Apoptosis

Visual performance

upin mice1

1 study
  1. Chitosan-rapamycin carbon dots improve visual performance in mice.

    “Functional assessments further confirmed superior visual performance in CRCD-Sca-1+ chimeras, correlating with improved RGC survival.”

    Animalspretreated autologous bone marrow stem cell transplantation in aged OPTN(E50K) miceretina

    Chitosan-rapamycin carbon dots rejuvenate autologous Sca-1⁺ stem cells paracrine function for neuroprotection in normal tension glaucoma

    Stem cell research & therapy23 Feb 2026

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