Chewing tobacco
Intervention2 papers4 findings
- In silico2
Outcomes
1Mortality
upin humans2Low certainty
2 studies
Mortality
upin humans2Low certainty
Chewing tobacco increases mortality in humans (251 thousand deaths (149-389) in 2023).
Humans1990-2023
Global, regional, and national burden of exposure to chewing tobacco, 1990-2023: a systematic analysis of the Global Burden of Disease Study 2023 · The Lancet. Global health · 1 Oct 2026
Chewing tobacco increases mortality in humans (+153.7% deaths, +124.8% DALYs).
Humanschewing tobacco
Tobacco-attributable mortality and disease burden in India: a descriptive analysis of Global Burden of Disease 2023 estimates for 1990 and 2023 · BMJ open · 30 Sep 2026
Associations
2Lip and oral cavity cancer
upin humans1Low certainty
1 study
Lip and oral cavity cancer
upin humans1Low certainty
Chewing tobacco raises the risk of lip and oral cavity cancer in humans (17·4 [11·3-24·3] DALYs per 100 000).
Humans1990-2023
Global, regional, and national burden of exposure to chewing tobacco, 1990-2023: a systematic analysis of the Global Burden of Disease Study 2023 · The Lancet. Global health · 1 Oct 2026
Stroke
upin humans1Low certainty
1 study
Stroke
upin humans1Low certainty
Chewing tobacco raises the risk of stroke in humans (55·9 [29·0-92·9] DALYs per 100 000 individuals).
Humans1990-2023
Global, regional, and national burden of exposure to chewing tobacco, 1990-2023: a systematic analysis of the Global Burden of Disease Study 2023 · The Lancet. Global health · 1 Oct 2026