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Chemogenetic activation of VTA GABA neurons

Intervention

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: Nederlandse Organisatie voor Wetenschappelijk Onderzoek
  • Animals1

Outcomes

1

Running wheel activity

downin mice1

1 study

  1. Chemogenetic activation of VTA GABA neurons decrease running wheel activity in mice.

    “Restoring the excitability of VTA GABA neurons via chemogenetic activation rescued mice from starvation, by decreasing running wheel activity.”

    Animalsin activity-based anorexia (ABA) modelventral tegmental area

    Reduced GABA transmission onto ventral tegmental area dopamine neurons underlies vulnerability for hyperactivity in a mouse model of Anorexia Nervosa

    bioRxiv (Cold Spring Harbor Laboratory)14 Mar 2024Preprint

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