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CB3

Intervention

1 paper studies it2 findings

PubChemChEBI

Across all fields, 1 paper: none in people yet, 1 in cells

More peptides

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Centre National de la Recherche Scientifique and 4 more
  • Cells1

Outcomes

2

Cell proliferation

upin mouse cells1

1 study

  1. CB3 improves cell proliferation in mouse cells.

    “chronic treatment with CB3, a thioredoxin-1 mimetic anti-inflammatory peptide, completely prevents p21CIP1 increase and enables day 14 macrophages to maintain proliferative activity”

    Cellsmacrophages cultured for 14 daysperitoneal macrophage

    A new model and precious tool to study molecular mechanisms of macrophage aging

    Aging

CDKN1A

downin mouse cells1

1 study

  1. CB3 inhibits CDKN1A in mouse cells.

    “chronic treatment with CB3, a thioredoxin-1 mimetic anti-inflammatory peptide, completely prevents p21CIP1 increase”

    Cellsmacrophages cultured for 14 daysperitoneal macrophage

    A new model and precious tool to study molecular mechanisms of macrophage aging

    Aging

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