Cannabinol

Intervention

3 papers study it4 findings

PubChemChEBIMeSH

  • 1 lab in 1 country
  • Funders: National Cancer Institute and 4 more
  • Animals1
  • Cells1

Outcomes

4

Synaptic transmission

upin mice1

1 study
  1. Cannabinol improves synaptic transmission in mice.

    “CBN upregulates key synaptic proteins involved in vesicle trafficking and postsynaptic signaling suggesting that it enhances synaptic function”

    Animalsaccelerated aging

    Cannabinol (CBN) alleviates age-related cognitive decline by improving synaptic and mitochondrial health

    Redox biologyMay 20, 2025

More on Synaptic transmission

Mitochondrial biogenesis (PGC-1α)

upin mice1

1 study
  1. Cannabinol activates mitochondrial biogenesis (PGC-1α) in mice.

    “upregulating markers of mitochondrial biogenesis including mitochondrial transcription factor A (TFAM) and translocase of outer mitochondrial membrane 20 (TOM20).”

    Animalsaccelerated aging

    Cannabinol (CBN) alleviates age-related cognitive decline by improving synaptic and mitochondrial health

    Redox biologyMay 20, 2025

More on Mitochondrial biogenesis (PGC-1α)

Energy expenditure

upin mice1

1 study
  1. Cannabinol increases energy expenditure in mice.

    “enhanced oxygen consumption and energy expenditure”

    Animalsaccelerated aging

    Cannabinol (CBN) alleviates age-related cognitive decline by improving synaptic and mitochondrial health

    Redox biologyMay 20, 2025

Spatial learning and memory

upin mice1

1 study
  1. Cannabinol improves spatial learning and memory in mice.

    “CBN significantly improves spatial learning and memory, with more pronounced cognitive benefits observed in female mice.”

    Animalsaccelerated aging

    Cannabinol (CBN) alleviates age-related cognitive decline by improving synaptic and mitochondrial health

    Redox biologyMay 20, 2025

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