Cannabinoids

Cannabinoids has been studied in 13 papers since 2019: 1 observational study in people, 12 reviews; 8 in the past year. Its furthest trials in people are at phase 2. The newest paper, Oct 29, 2026: “The Effects of Cannabinoids in Cardiovascular Disease: A Comprehensive Review”.

InterventionPhase 2

13 papers study it143 more mention it4 findingsUpdated

PubChemMeSH

7 new papers in 30 daysSee all 155 papers on cannabinoids

At a glance

The findings reach people, from one lab or study. 1 lab in 1 country; 3 trials, none about aging.

“Memantine, opioids, cannabinoids, prior history of fall, female sex, advanced age and disease stage, chronic liver disease, diabetes, and chronic obstructive pulmonary disease all increased the hazard rate of falling.”
The associations of oxaliplatin-induced peripheral neuropathy, sociodemographic characteristics, and clinical characteristics with time to fall in older adults with colorectal cancerAmerican journal of epidemiology2024doi:10.1093/aje/kwae067
Humans: a single group. Cells, worms or flies and mice: nothing yet.
  • 1 lab in 1 country
  • 3 trials, none about aging
  • Funder: National Cancer Institute
  • Humans1

What did studies of cannabinoids find?

3

Studies of cannabinoids measured 3 outcomes: behavioral symptoms, oxidative stress and ROS signaling and inflammation.

Behavioral symptoms

upin humans1

1 study
  1. Cannabinoids improve behavioral symptoms in humans.

    “Cannabinoids improved behavioral symptoms but showed no measurable cognitive effects.”

    Review

    Dietary Bioactives in Alzheimer's Disease: A Critical Appraisal of Clinical Trials and Future Nutritional Strategies

    Nutrients

Oxidative stress and ROS signaling

downin reviews1

1 study
  1. Cannabinoids decrease oxidative stress and ROS signaling.

    “cannabinoids, as components of the cannabinoid system (CS), have proven beneficial effects such as anti-inflammatory, immunomodulatory, neuromodulatory, antioxidative, and cardioprotective effects.”

    Review

    The Therapeutic Potential of the Endocannabinoid System in Age-Related Diseases

    Biomedicines

More on Oxidative stress and ROS signaling

Inflammation

downin reviews1

1 study
  1. Cannabinoids decrease inflammation.

    “cannabinoids, as components of the cannabinoid system (CS), have proven beneficial effects such as anti-inflammatory, immunomodulatory, neuromodulatory, antioxidative, and cardioprotective effects.”

    Review

    The Therapeutic Potential of the Endocannabinoid System in Age-Related Diseases

    Biomedicines

More on Inflammation

What is cannabinoids linked with?

1

Studies link cannabinoids with falls.

Falls

upin humans1

1 study
  1. Cannabinoids are linked with a higher risk of falls in older patients with colorectal cancer.

    “Memantine, opioids, cannabinoids, prior history of fall, female sex, advanced age and disease stage, chronic liver disease, diabetes, and chronic obstructive pulmonary disease all increased the hazard rate of falling.”

    Humansin older patients with colorectal cancer

    The associations of oxaliplatin-induced peripheral neuropathy, sociodemographic characteristics, and clinical characteristics with time to fall in older adults with colorectal cancer

    American journal of epidemiology

Has cannabinoids been tested in people?

0 of 3 about aging

Yes: 1 observational study in people have been published, and 3 trials are registered.

In trials

Stopped

  • NCT03782402TerminatedChemotherapy induced peripheral neuropathy

    Funding being sought

Trial sponsors

Latest

Dec 2025: 5Jan 2026: 3Feb 2026: 10Mar 2026: 6Apr 2026: 1May 2026: 5Jun 2026: 3Jul 2026: 4Aug 2026: 0Sep 2026: 1Oct 2026: 7Nov 2026: 247 papers in 12 months

See all 155 papers on cannabinoids